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An anonymous reader quotes a report from The Guardian: Miniature human organs and other tissues are to be grown from NHS patients' cells in a drive to improve medicine testing and reduce the number of animals used in drug development. Scientists will use the clumps of tissue to learn how diseases vary between patients, helping them identify which treatments are best for different people based on the particular pathology underlying their condition. The move marks a shift away from the traditional use of animals as models for human disease, towards what researchers believe will be more accurate and reliable tests based directly on human tissues. Researchers have been growing tiny clumps of human organs, known as organoids, for more than a decade. Tests show that pieces smaller than a millimeter can mirror key features of full-scale organs and tissues, including how they falter with disease and respond to drugs. Armed with organoids grown from diseased human tissues, scientists can investigate whether new drug candidates reverse pathological changes in all or a subset of patients, and quickly identify ineffective drugs early in the process. Historically, more than 90% of drugs that clear animal testing go on to fail in human trials, raising questions about the value of the tests. US and European medicines regulators now encourage other approaches if available. "It's going to have a major impact on the numbers of animals used and the way we develop new drugs in the future," said Matthias Zilbauer, a clinical professor of paediatric gastroenterology at the Cambridge Stem Cell Institute. "We're not saying there won't be any animal use in the near or foreseeable future, because there are still certain issues that cannot be tested in these new models, but the reduction is very real." "A lot of human diseases either do not occur in animals or occur in a different way because they're not human," added Zilbauer. "We want tests and models that can tell us which treatments work, and in what patients, and a mouse cannot tell us that." 
Read more of this story at Slashdot. - Microsoft Retreats In China Microsoft has been steadily scaling back its China presence, closing at least 15 branch offices and joint ventures over the past five years as Beijing favors domestic software. U.S. export controls also make it harder to grow its cloud and AI businesses, leaving the market with relatively little economic upside. Reuters reports: Microsoft took a major hit from the erosion of trust between Washington and Beijing, the five people said. China has since 2017 pushed the use of domestic software, which Beijing sees as more secure and whose quality is increasingly competitive with Windows and Office. U.S. restrictions, including export controls on advanced technology, have meanwhile hindered efforts to scale Microsoft's lucrative AI and cloud businesses in China. [...] Microsoft ultimately decided to remain because it had carved out a profitable business servicing Chinese companies like TikTok owner ByteDance, which need Western technology to manage overseas operations, according to three people familiar with the matter. The company also believed that it needed a presence to maintain access to China's world-class engineering talent, two of them said. Microsoft had also cultivated a relationship with the government that is among the deepest of any tech company, its former China head Alain Crozier told Reuters. "Because of the geopolitics ... some days it's a little bit harder, but we never had a crisis," he said. A Microsoft spokesperson did not address questions about the firm's deliberations on its China business but said it operates in a regulatory "environment that applies to every international supplier" and that it remains committed to the Chinese market. The state of Microsoft's China business reflects market competition, regulatory demands and technological trends, the company said.
Read more of this story at Slashdot. - Google's Gemini 3.7 Flash Targets Coding and Agents With a 50% Price Cut Google has released Gemini 3.7 Flash just three weeks after 3.6 Flash, focusing on better coding, agentic workflows, and enterprise automation while temporarily cutting API prices in half through the end of 2026. VentureBeat reports: For enterprise developers, the more consequential story may be the combination of those intelligence gains with lower inference costs: through the end of 2026, Gemini 3.7 Flash costs $0.75 per million input tokens and $3.75 per million output tokens. Starting Jan. 1, 2027, pricing rises to $1.50 per million input tokens and $7.50 per million output tokens. That means the current discount is temporary, but it gives teams deploying high-volume coding and business agents several months to evaluate whether Google's claimed reductions in retries and manual oversight translate into lower total operating costs. The launch also underscores Google's rapid iteration on its Flash line while its next flagship Pro model remains absent. [...] Google describes Gemini 3.7 Flash as its "most intelligent workhorse model yet for coding and agents." The company says the model is better at adapting when it encounters roadblocks, clarifying intent when necessary and following instructions with greater fidelity. [...] Google's benchmarks show a large generational improvement in several software engineering tests. [...] Google's own results do not show 3.7 Flash universally displacing higher-priced competitors. They instead suggest a model that has become substantially more competitive in coding and agent workloads while occupying a lower price tier.
Read more of this story at Slashdot. - Microsoft Is Combining Its Copilot Apps Ahead of a 'Super App' Microsoft is merging its consumer Copilot and Microsoft 365 Copilot apps ahead of a broader "super app" launch later this year. "Both personal and work accounts will be moved to the new unified app, which recycles the 'Microsoft Copilot' name but features an updated app icon," reports The Verge. "The single app also means there won't be two annoying Copilot icons in the system tray or taskbar anymore." From the report: The updates are intended to be a technical milestone in preparation of the "super app" Microsoft is planning to launch later this year, so this is laying the foundations of what will be changing for Copilot products. A worldwide rollout for the mobile and web apps will start in "mid-August," according to Microsoft, with a rollout to Windows and Mac apps set for "mid-September." Mobile app users will be prompted to download the new Copilot app, and the updates will start appearing for some Windows Insiders this week. What changes you'll see will depend on which Copilot apps you're already using. Existing Microsoft Copilot users will be moved to the updated version, along with your chats and content, while Microsoft 365 Copilot app users will see "minor navigation changes," the updated Copilot icon, and gain access to Copilot chat. If you already use both apps, Microsoft says your chats and content will be merged to a single updated Copilot app, but notes that chats, content, and data will remain separate between account types within the app. Microsoft says enterprise security, compliance, and government controls will remain unchanged and core Copilot features will remain free, though usage limits may vary. Podcasts, Deep Research, and Group Chat content will, however, be discontinued after August 18. The company also says Shopping and Copilot Health "may be temporarily unavailable" during the transition.
Read more of this story at Slashdot. - Amazon Will Train On Twitch Streamers' Content By Default, Unless They Opt Out Twitch will begin allowing Amazon to use streamers' content to train generative AI models by default, requiring creators to manually opt out if they don't want their videos and audio included. The decision has drawn backlash from creators, with Twitch's own product chief acknowledging that an opt-in system would likely attract almost no participants. "Why is it not opt-in? That's what everybody is spamming in chat. I get it. 'Let me opt in versus making me opt out,'" said Twitch Chief Product Officer Mike Minton. "Well, there's an honest answer... If this was opt-in, nobody would opt in. That's honestly the answer." TechCrunch reports: For Amazon, these stream recordings are incredibly valuable, offering thousands of hours of audio and video content to help train AI models. But Twitch users worry that since creators have to manually opt out, they might be surrendering their content to train Amazon's AI content models without even knowing it. This is especially concerning on a platform like Twitch, where creators are often recording livestreams of themselves and their voices for many hours per week. [...] Twitch knows that its community of streamers is largely opposed to the use of generative AI, since the most prevalent generative AI products are trained on books, images, videos, and other materials scraped from the internet without consent. Even Twitch's approach to breaking this news shows that the company is braced for backlash. Instead of telling the community that Amazon would begin training on Twitch users' content, Twitch framed this change as "[adding] a setting that lets you opt out of having your channel content used to train generative AI content models across Amazon." In some cases, this created confusion among streamers about whether their content had already been fed to Amazon without their knowledge. When one user asked if their videos had already been used for training, Minton responded, "I don't actually know the answer to that question because I don't know what Amazon [...] has done in terms of model training and what they've used and not used."
Read more of this story at Slashdot. - Anthropic Could Be Worth $2 Trillion When It Goes Public An anonymous reader quotes a report from the Financial Times: Anthropic investors expect the AI startup to float at a valuation of $2 trillion or more in October, a dizzying figure that would eclipse SpaceX and make the AI lab's debut the largest-ever initial public offering. Half a dozen of the company's backers told the FT that Anthropic's rapidly rising revenue would enable it to more than double its current valuation in a planned autumn float. A listing at that level could unlock billions of dollars in gains for the five-year-old company's early investors but would also test public markets that are growing more nervous about the AI boom. Anthropic's backers say booming demand for the lab's advanced AI models and tools justifies their lofty expectations. Investors expect the Claude maker's annualized revenue to be between $100 billion and $120 billion by the end of 2026 -- using the startup's preferred measure, which infers full-year sales from recent performance -- up by more than 10 times over the course of 2026. "If Anthropic is growing 800 percent a year, you'd think at the incredibly low end they would trade at 30 times [revenue]," said one investor in the group. "That would make them a $3 trillion company." According to Bloomberg (paywalled), Anthropic is currently in talks to acquire Decart AI for roughly $6 billion. "Decart develops world models alongside software designed to lower AI training expenses by improving how efficiently chips are utilized," reports Quartz. "That capability could allow Anthropic to get more out of its current infrastructure as demand grows. If the deal closes, Decart's team would join Anthropic's inference and performance organization."
Read more of this story at Slashdot. - World's Largest 106-Foot Electric Plane Takes Maiden Flight In New York Heart Aerospace's X1, billed as the world's largest battery-electric aircraft, completed a 27-minute maiden flight in New York using more than 1 MW of power and only about $5 worth of electricity. The 106-foot-wingspan demonstrator is a precursor to the company's 30-seat hybrid-electric ES-30 regional airliner, targeted for service in 2031. Interesting Engineering reports: Developed by Heart Aerospace, the X1 demonstrator lifted off from Plattsburgh International Airport in New York on Wednesday, August 12. The piloted aircraft remained in the skies for about 27 minutes and made it to a 1,100-foot altitude above ground level (AGL). According to the Swedish aerospace company, the aircraft has a wingspan of 106 feet (32 meters). It's additionally 76 feet (23 meters) long and has a takeoff weight exceeding 25,000 lbs (11,340 kilograms). "With the first flight of X1, Heart Aerospace has demonstrated electric flight at the scale of a commercial airliner," said Anders Forslund, Heart Aerospace founder and CEO. "Electric commercial aircraft have the potential to fundamentally reshape airline economics and, ultimately, lower the cost ofÂair travelÂfor passengers." "This is at the heart of our vision for abundant air travel, with electrification enabling more affordable, frequent, and cleaner air service to and from airports closer to home." You can watch the first flight on YouTube.
Read more of this story at Slashdot. - Apple Turns to Publishers For Help With Siri AI Apple is reportedly negotiating multi-year deals with news publishers to give its redesigned Siri access to current news and other information, with payments potentially tied to how often publishers' content is used. The talks come as Apple prepares to launch its long-delayed Siri AI later this year, after partnering with Google to use distilled Gemini models. Engadget reports: [The Wall Street Journal] did not reveal the specific publishers Apple reached out to, but did note the company has proposed structuring payments around a variable compensation plan, which would see it pay those organizations when their content is used. By contrast, most large AI labs like OpenAI have typically offered guaranteed fees in exchange for broad access. According to the The Journal, Apple has paid publishers for access to their content in the past as part of earlier agreements that saw the company secure AI training rights.
Read more of this story at Slashdot. - University of Michigan Drops First-Semester Grades to 'Curb Mental Health Crisis' "In order to salve the mental health of freshman students, the University of Michigan has implemented a Pass/No Credit system for new students to improve their mental health," writes Slashdot reader Ol Olsoc. "The process, called 'Grade Covering,' is aimed at helping with the mental health crisis that students face by lessening grade pressure." Axios reports: U-M's College of Literature, Science and the Arts plans to replace first-semester letter grades on freshmen's transcripts with pass/no-credit marks, tentatively beginning in fall 2027. Professors would still assign grades, but they wouldn't appear on external transcripts or count toward students' GPAs. U-M says the idea, known as "grade covering," could help students adjust to college, take academic risks and "embrace the joy of learning." University spokesperson Chris Sebastian tells Axios that LSA faculty, staff and students will continue shaping the pilot, with more details to come this fall. "While I am sure that there is some pressure on freshman students, one of the best ways of dealing with pressure is enduring it and overcoming it, not attempting to shield people from it," comments Ol Olsoc.
Read more of this story at Slashdot. - VA Launches Psilocybin Trial For Veterans With Treatment-Resistant Depression Longtime Slashdot reader sbinning shares a press release: The U.S. Department of Veterans Affairs announced the launch of a new clinical trial to evaluate the effectiveness and safety of psilocybin to treat major depression in Veterans, including those with concurrent PTSD. The new trial comes after a recent executive order on "Accelerating Medical Treatments for Serious Mental Illness," which aims to increase clinical trial participation and accelerate innovative research models and drug approvals for psychedelic drugs. [...] The randomized, controlled trial will enroll Veterans diagnosed with treatment-resistant major depressive disorder, with or without concurrent PTSD, and will compare outcomes between two psilocybin dosage levels. The study will also assess participants' levels of depression before and after treatment, tolerability of side effects, and overall patient-reported depression. [...] In addition to this trial, VA is involved in 20 active clinical trials focused on psychedelic therapies for mental health conditions. All VA research -- including research into psychedelics -- is conducted under strict safety protocols and in full compliance with federal guidelines.
Read more of this story at Slashdot. - Scientists Create Largest 2D Map of the Universe After 13 years of observations and data processing, astronomers have released the largest two-dimensional map of the universe ever assembled, "offering a sweeping new view of nearly 4 billion celestial objects across roughly three-quarters of the sky," reports Space.com. From the report: The new map, created by the Dark Energy Spectroscopic Instrument (DESI) Legacy Imaging Surveys team, contains a staggering 5.6 trillion pixels and combines more than 263,000 telescope exposures collected over more than a decade. The observations span visible and near-infrared wavelengths, providing an enormous portrait of stars, galaxies and other cosmic phenomena across the sky, according to a statement from the National Science Foundation (NSF) NOIRLab. "It's part of the fabric of astronomy research now," David Schlegel, co-lead of the Legacy Surveys and a scientist at the U.S. Department of Energy's Lawrence Berkeley National Laboratory, said in a statement. "When you're working with astronomical objects today, you often start by pulling up the Legacy Imaging Viewer to see what you're looking at."
Read more of this story at Slashdot. - How Social Media Spurred a Refugee Crisis Between Spain and Morocco An anonymous reader quotes a report from The New York Times: Two days before tens of thousands of migrants surged into Ceuta, one of Spain's enclaves on Morocco's northern coast, a newspaper there posted a video on TikTok and Instagram showing two young women walking in the city in wet suits, their hair still damp. The posts didn't say so explicitly, but the implication was clear: The women had just swum across the border from Morocco. "Ceuta can't take it anymore," the newspaper, El Faro de Ceuta, declared in the posts. On the other side of the border, the video resonated very differently. Cropped and reposted in Arabic, the video seemed like an invitation. The women were smiling, flashing peace signs and thumbs up and, most of all, walking around freely. The video seemed to legitimize rumors that had percolated for weeks on social media suggesting that a recent ruling by Spain's Supreme Court meant migrants who arrived illegally by sea could stay in the country. As one account on Facebook put it, falsely, "Ceuta is turning into an open gate," when in fact migrants still faced expulsion after a judicial review. The responses to the posts about the swimmers were a critical part of a cascade of disinformation that experts described as one of the starkest instances in which social media contributed directly to a real-world tragedy.
Read more of this story at Slashdot. - Trump Administration Enlists Private Companies To Hack Foreign Cybercrime Groups The Trump administration today unveiled a new program that will allow vetted U.S. companies to conduct cyber surveillance and offensive cyber operations against foreign transnational criminal organizations. A presidential memorandum signed August 12 directs the National Coordination Center to establish and manage the program, expanding the government's fight against cybercrime by tapping the technical capabilities of the private sector. It builds on a March executive order that called for greater private-sector involvement, but goes significantly further by establishing a formal operational framework for the initiative. The White House argues that American companies possess a "critical offensive cyber advantage" whose capabilities have "historically been underutilized" in efforts to identify and disrupt criminal networks operating online. There are two broad categories of authorized activity. "Cyber Surveillance Operations" can involve secretly accessing foreign information systems without authorization to gather intelligence, including information that could later be used for offensive operations. "Cyber Effects Operations," meanwhile, can result in the "manipulation, disruption, denial, degradation, or destruction" of information systems, networks, or infrastructure. It's worth noting that companies will not be free to launch their own operations. The memorandum requires program officials to "review every cyber operations package and provide written approval and direction" before a participating company can act. Operations that could cause death or serious injury, or "rise to the level of use of force or armed attack under international law," are classified as "Critical Outcomes" and cannot be approved through the standard process. The program includes safeguards requiring companies to halt and report operations that unintentionally affect U.S. persons or systems, as well as any imminent threats to critical infrastructure.
Read more of this story at Slashdot. - Big Tech Wants to Harvest Your Thoughts Wired reports that consumer neurotechnology is rapidly moving from the lab into workplaces and homes, with companies including Apple, Meta, and Snap developing products that can monitor or interpret brain activity. Researchers warn that as these systems improve, neural data could become the next major privacy battleground. Some neuroscientists are already calling for a series of core rights, coined "neurorights," that protect "mental privacy," "identity," and personal "agency." Here's an excerpt from the article: Over the past two decades, researchers using functional magnetic resonance imaging (fMRI), which tracks the iron in the hemoglobin supplying oxygen to neurons, have been building up increasingly detailed maps and inventories of the mammalian cortex. Thanks to huge advances in machine-learning artificial intelligence -- computer algorithms that are able to sort through enormous amounts of information and use statistical methods to make classifications and predictions -- fMRI scans can now be used to identify everything from depressive thoughts to the nuanced feelings of envy and schadenfreude. Other algorithms have been able to accurately piece together reconstructions of movie clips watched by subjects, just by analyzing their brain scans; or have detected, in probing the brain activity of swing voters in the US presidential election, responding to photographs and videos of presidential candidates, which candidates provoked anxiety or even disgust, and which elicited positive responses or feelings of empathy. In just the last few years, neuroscience researchers have progressed from decoding images and emotions as they play across the cortex to sounds, words, phrases, and even language. In 2023, in a remarkable demonstration of this emerging technology, a woman called Ann Johnson, who had been paralyzed for 18 years by a brain-stem stroke, was able to speak again through the insertion of a grid of 253 electrodes onto the surface of her brain, which translated her neuronal signals into sentences, in real time, at a rate of 78 words per minute (just about half the speed of standard conversation). The research team at the University of California, led by neurosurgeon Edward Chang, had combined this brain-computer interface with an animated avatar of Johnson's head, which spoke in her own voice, as reconstructed from a recording of a 15-minute toast she had given at her wedding. Just as the avatar's mouth spoke Johnson's words as she thought them, so its expressions were similarly influenced by the nuances of her brain activity, which turned her thoughts about facial gestures into displays of emotion -- from smiles to pursed lips and frowns. [...] The more invasive the recording equipment, the richer and more detailed the data. Surgical interventions are at the vanguard of neuroscience and remain very rare -- fewer than 100 people on the planet have brain-computer interfaces like Johnson's embedded beneath their skulls. Yet almost inevitably, a concerted trickle-down effect is occurring. In the summer of 2023, a team at the University of Texas demonstrated that they could use fMRI to translate brain scans into words and sentences, after subjects listened to 16 hours of the storytelling podcasts The Moth Radio Hour and The New York Times' Modern Love to train an AI model. When the subjects then listened to new podcasts, the algorithm was able to convert the gist of what they heard, as it manifested in their brains, into words, phrases, and sentences that roughly captured the stories. As the team's lead computational neuroscientist, Alexander Huth, put it in an interview with Science, "Our thought when we actually had this working was, 'Oh my God, this is kind of terrifying.'" Now noninvasive, wearable brain scanners are beginning to proliferate beyond the lab, making their way into our workplaces and, through the vast global consumer market, into our homes too.
Read more of this story at Slashdot. - 'Godmother of AI' Says Biggest AI Risk In Schools Is Students Losing the Desire to Learn Fei-Fei Li, aka The Godmother of AI, says the biggest AI risk in education may be students losing the motivation and agency to learn, rather than simply using the technology to cheat. She argues against banning AI outright, saying it can be valuable when used to support engaged students instead of replacing the thinking and struggle that learning requires. Techspot reports: Speaking on an episode of the science podcast Huberman Lab this week, Li talked about the fears around how students are using AI. "The absolute bad outcome is that our young generation, their agency and human-level motivation of learning and living is taken away by tools," the ImageNet inventor warned. "It should not be taken away by humans nor should it be taken away by machines." If we see a generation of graduates who have completely relied on AI without actively trying to learn anything for themselves, they risk leaving education without having "properly developed the brain," Li said. [...] Li certainly isn't advocating for a complete ban on students using AI. She believes it can genuinely help struggling students who are already engaged in their learning. Li herself noted how she struggled with organic chemistry as a premed student, when teaching assistants and professors didn't have enough time to answer every question. While there's no obvious solution, Li says we need to find a way to keep children and students' motivation and agency. "Let's find a way to give them the access and the right way of using these tools," she said. Li added that if AI is used properly in education, it could make the students of the future "way smarter than us because they are superpowered."
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